A web-based personalized decision support tool for patients diagnosed with ductal carcinoma in situ: development, content evaluation, and usability testing

Fridman I (a), Chan L (a), Thomas J, Fish LJ, Falkovic M, Brioux J, Hunter N, Ryser DH, Hwang ES, Pollak KI, Weinfurt K, Ryser MD

(a) contributed equally

Breast Cancer Research and Treatment, acceepted (2022)


A Bayesian hierarchical model to estimate DNA methylation conservation in colorectal tumors

Murgas KA, Ma Y, Shahidi LK, Mukherjee S, Allen AS, Shibata D, Ryser MD

Bioinformatics, online first (2021)

DCIS: State of the Art Review

Grimm L, Rahbar H, Abdelmalak M, Hall A, Ryser MD

Radiology, accepted (2021)

Long-term risk of subsequent ipsilateral lesions after surgery with or without radiotherapy for ductal carcinoma in situ of the breast

van Seijen M, Lips EH, Fu L, Giardiello D, van Duijnhoven F, de Munck L, Elshof LE, Thompson A, Sawyer E, Ryser MD, Hwang ES, Schmidt MK, Elkhuizen PHM, Wesseling J, Schaapveld M

British Journal of Cancer, 125.10: 1443-1449 (2021)


Association of combined sero-positivity to Helicobacter pylori and Streptococcus gallolyticus with risk of colorectal cancer

Epplein E, Le Marchand L, Cover T, Song M, Blot W, Peek W, Teras L, Visvanathan K, Chen Y, Sesso H, Zeleniuch-Jacquotte A, Berndt S, Potter J, Ryser MD, Haiman C, Wassertheil-Smoller S, Tinker L , Waterboer T, Butt J

Microorganisms, accepted (2020)

Auto-antibodies to p53 and the subsequent development of colorectal cancer in a United States prospective cohort consortium

Butt J, Blot WB, Visvanathan K, Le Marchand L, Wilkens LR, Chen Y, Sesso HD, Teras LR, Ryser MD, Hyslop T, Wassertheil-Smoller S, Tinker LF, Potter JD, Song M, Berndt SI, Waterboer T, Pawlita M, and Epplein M

Cancer Epidemiology, Biomarkers & Prevention, accepted (2020)

Time-varying survival effects for squamous cell carcinomas at oropharyngeal and non-oropharyngeal head and neck sites in the United States, 1973–2015

Brouwer AF, He K, Chinn SB, Mondul AM, Chapman CH, Ryser MD, Banerjee M, Eisenberg MC, Meza R, Taylor JMG

Cancer, accepted (2020)

Risk of Malignant Upgrade After Breast Core Needle Biopsy Diagnosis of Lobular Neoplasia: A Systematic Review and Meta-Analysis

Shehata MN, Rahbar H, Flanagan MR, Kilgore MR, Lee CI, Ryser MD, Lowry KP

Journal of the American College of Radiology, accepted (2020)

Relationship Between HCAHPS Scores and Survey Response Rate Is Linked to Hospital Size

Rodriguez-Homs LG,Hammill BG, Ryser MD, Phillips HR, Mosca, PJ

Journal of Patient Experience, online first (2020)

Withdrawal of Life-Supporting Treatment in Severe Traumatic Brain Injury: Evidence for Regional and Socioeconomic Variation

Williamson T, Ryser MD, Ubel PA, Abdelgadir J, Spears CA, Liu B, Komisarow J, Lemmon ME, Elsamadicy A, Lad SP

JAMA Surgery, online first (2020)

Modeling the natural history of ductal carcinoma in situ based on population data

Chootipongchaivat S, van Ravesteyn NT, Li X, Huang H, Weedon-Fekjær H, Ryser MD, Weaver D, Burnside ES, Heckman-Stoddard BM, de Koning HJ, Lee SJ

Breast Cancer Research, 22:53 (2020)

Minimal Barriers to Invasion During Human Colorectal Tumor Growth

Ryser MD, Mallo D, Hall A, Hardman T, King LM, Tatishchev S, Sorribes IC, Maley CC, Marks JR, Hwang ES, Shibata D

Nature Communications, 11:1280 (2020)

Surgical Decision Making in the Setting of Severe Traumatic Brain Injury: A Survey of Neurosurgeons

Williamson T, Ryser MD, Lemmon M, Abdelgadir J, Barks MC, Zakare R, Ubel PA

PLoS ONE 15(3): e0228947 (2020)


Response to Habel and Buist

Ryser MD, Hwang ES

Journal of the National Cancer Institute, djz120 (2019)

Incidence of Ductal Carcinoma in Situ in the United States, 2000-2014

Ryser MD, Hendrix L, Worni M, Liu Y, Hyslop T, Hwang ES

Cancer Epidemiology, Biomarkers and Prevention, 28(8):1316-1323 (2019)

Growth dynamics of mammographic calcifications: differentiating ductal carcinoma in situ from benign breast disease

Grimm LJ, Miller M, Lo J, Hyslop T, Hwang ES, Ryser MD

Radiology, 292(1):77-83 (2019)

Cancer outcomes in DCIS patients without locoregional treatment

Ryser MD, Weaver DL, Zhao F, Worni M, Grimm L, Gulati R, Etzioni R, Hyslop T, Lee SJ, Hwang ES

Journal of the National Cancer Institute, 111(9): djy220 (2019)


Epigenetic heterogeneity in human colorectal tumors reveals preferential conservation and evidence of immune surveillance

Ryser MD, Yu M, Grady W, Siegmund K, Shibata D

Scientific Reports, 8:17292 (2018)

Identification of the fraction of indolent tumors and associated overdiagnosis in breast cancer screening trials

Ryser MD, Gulati R, Eisenberg MC, Shen Y, Hwang ES, Etzioni RB

American Journal of Epidemiology, 188(1):197–205 (2018)

Estimating the frequency of indolent breast cancer in screening trials

Shen Y, Dong W, Gulati R, Ryser MD, Etzioni RB

Statistical Methods in Medical Research, 28(4):1261–1271 (2018)

Spatial mutation patterns as markers of early colorectal tumor cell mobility

Ryser MD, Min BH, Siegmund KD, Shibata D

Proceedings of the National Academy of Sciences, 115(22):5774-5779 (2018)

How Low Can We Go - and Should We? Risk Reduction for Minimal-Volume DCIS

Ryser MD, Horton J, Hwang ES

Annals of Surgical Oncology, 25:354-355 (2018)

Pre-operative variables are critical in reducing the rate of occult invasive disease for women considering active surveillance for DCIS.

Grimm LJ, Ryser MD, Hyslop T

JAMA Surgery, 153(3):290-291 (2018)


Dissecting age-specific HPV seroprevalence in US women: The role of cohort effects and waning immunity

Ryser MD, Rositch AF, Gravitt PE

The Journal of Infectious Diseases, 216(5):604-611 (2017)

Programmed assembly of pressure sensors using pattern-forming bacteria

Cao Y, Feng Y, Ryser MD, Zhu K, Herschlag G, Marusak K,Zauscher S, You L

Nature Biotechnology, 35:1087-1093 (2017)

Mechanistic Mathematical Models: An Underused Platform for HPV Research

Ryser MD, Gravitt PE, Myers ER

Papillomavirus Research, 3:46-49 (2017)

Bone remodeling as a spatial evolutionary game

Ryser MD and Murgas KA

Journal of Theoretical Biology 418(7):16-26 (2017)

Surgical upstaging rates for vacuum assisted biopsy proven DCIS: implications for active surveillance trials

Grimm LJ, Ryser MD, Partridge AH, Thompson AM, Thomas JS, Hwang ES

Annals of Surgical Oncology, 24(12):3534-3540 (2017)


Spatial measures of genetic heterogeneity during carcinogenesis

Storey K, Ryser MD, Leder KZ, Foo J

Bulletin of Mathematical Biology, 79(2): 237-276 (2016)

Quantifying the dynamics of field cancerization in tobacco-related head and neck cancer: a multi-scale modeling approach

Ryser MD, Lee WT, Ready NE, Leder KZ, Foo J

Cancer Research, 76(24):7078-7088 (2016)

Collective space sensing coordinates pattern scaling in engineered bacteria

Cao Y, Ryser MD, Payne S, Li B, Rao CV, You L

Cell 166(3): 620-630 (2016)

Outcomes of active surveillance for ductal carcinoma in situ: a computational risk analysis

Ryser MD, Worni M, Turner EL, Marks JR, Durrett R, Hwang ES

Journal of the National Cancer Institute, 108(5):djv372 (2016)


Trends in treatment patterns and outcomes for ductal carcinoma in situ (DCIS)

Worni M, Akushevich I, Greenup R, Sarma D, Ryser MD, Myers ER, Hwang ES

Journal of the National Cancer Institute, 107(12):djv263 (2015)

HPV clearance and the neglected role of stochasticity

Ryser MD, Durrett R, Myers ER

PLoS Computational Biology, 11(3):e1004113 (2015)

Impact of coverage-dependent marginal costs on optimal HPV vaccination strategies

Ryser MD, McGoff K, Herzog DP, Sivakoff DJ, Myers ER

Epidemics, 11:32-47 (2015)

Mathematical modeling of cancer metastases

Ryser MD and Komarova SV

in Computational Bioengineering, CRC/Taylor & Francis (2015)

Multifocality and recurrence risk: a quantitative model of field cancerization

Foo J, Leder K, Ryser MD

The Journal of Theoretical Biology, 355:170-184 (2014)

2014 and Earlier

Temporal control of self-organized pattern formation without morphogen gradients in bacteria

Payne S, Li B, Schaeffer D, Ryser MD, You L

Molecular Systems Biology, 9:697 (2013)

Triviality of the 2D stochastic Allen-Cahn equation

Hairer M, Ryser MD, Weber H,

Electronic Journal of Probability, Volume 17, Article 39 (2012)

On the well-posedness of the stochastic Allen-Cahn equation in two dimensions

Ryser MD, Tupper PF, Nigam N

Journal of Computational Physics, Volume 231, Issue 6, Pages 2537-2550 (2012)

Osteoprotegerin in bone metastases: mathematical solution to the puzzle

Ryser MD, Qu Y, Komarova SV

PLoS Computational Biology, Volume 8, Issue 10, e100270 (2012)

The cellular dynamics of bone remodeling: a mathematical model

Ryser MD, Nigam N, Komarova SV

SIAM Journal on Applied Mathematics, Volume 70, Issue 6, pp. 1899-1921 (2010)

Mathematical modeling of spatio-temporal dynamics of a single bone multicellular unit

Ryser MD, Nigam N, Komarova SV

Journal of Bone and Mineral Research, 24:860-870 (2009)

Inhomogeneous precipitation distribution and snow transport in steep terrain

Lehning M, Loewe H, Ryser MD, Raderschall N

Water Resources Research, 44, W07404 (2008)

Thermal quantum electrodynamics of non relativistic charged fluids

Buenzli PR, Martin PA, Ryser MD

Physical Review E, 75, 041125 (2007)

Ph.D. thesis: Of Bones and Noise

under the supervision of Nigam N, Tupper PF and Komarova SV

M.Sc. thesis: Electromagnetic Fluctuations in Charged Fluids Coupled to the Radiation Field.

under the supervision of Martin PA